Crockpot Dr. Pepper Meatloaf

Posted on January 8, 2026

Delicious Crockpot Dr. Pepper Meatloaf served on a plate with fresh vegetables

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This Crockpot Dr. Pepper Meatloaf is a fun twist on a classic dish! Adding Dr. Pepper gives it a sweet and tangy taste that makes every bite special.

I love how easy it is to throw everything in the slow cooker and let it do its magic. Plus, the smell that fills the kitchen while it cooks is just irresistible! 🍖

Key Ingredients & Substitutions

Ground Beef: I recommend 80/20 for a juicy meatloaf with good flavor. If you prefer a leaner option, 90/10 works too, but it may be a bit drier. You can also use ground turkey or chicken for a lighter version!

Dr. Pepper: This soda is key for sweetness and moisture. If you don’t have Dr. Pepper, root beer or another cola can provide a similar flavor. Just be mindful of the sugar content in alternatives!

Ketchup: It’s not just a topping—it’s part of the mix too! If you’re looking for a healthier option, try a low-sugar ketchup or make your own with tomato paste, vinegar, and a bit of honey.

Breadcrumbs: They help bind the meatloaf together. If you don’t have breadcrumbs, crushed crackers or oats can be good substitutes that still hold everything nicely.

How Do You Ensure Your Meatloaf Stays Moist?

One important technique is mixing the ingredients just until combined. Over-mixing can lead to a tough texture. Also, using the right liquids is essential.

  • Make sure to include milk and Dr. Pepper to keep the mixture moist.
  • Form the loaf gently without packing it too tightly; this helps prevent dryness.

Lastly, don’t skip the glaze! The last 30 minutes of cooking with the glaze makes the top deliciously sticky and adds moisture, enhancing the overall flavor and keeping the meatloaf tender.

Crockpot Dr. Pepper Meatloaf

Crockpot Dr. Pepper Meatloaf

Ingredients You’ll Need:

For the Meatloaf:

  • 2 pounds ground beef (preferably 80/20)
  • 1 cup breadcrumbs
  • 1 small onion, finely chopped
  • 2 cloves garlic, minced
  • 2 large eggs
  • 1/2 cup milk
  • 1/2 cup Dr. Pepper soda
  • 1/4 cup ketchup (plus more for topping)
  • 2 tablespoons Worcestershire sauce
  • 1 teaspoon salt
  • 1/2 teaspoon black pepper
  • 1/2 teaspoon dried thyme
  • 1/2 teaspoon dried oregano
  • 1/4 teaspoon smoked paprika (optional)

For the Glaze/Topping:

  • 1/2 cup ketchup
  • 1/4 cup Dr. Pepper
  • 2 tablespoons brown sugar
  • 1 tablespoon Dijon mustard (optional)
  • Fresh parsley, chopped (for garnish)

How Much Time Will You Need?

This tasty meatloaf takes about 15 minutes to prepare, and then you’ll let your crockpot do the magic! Cook on low for 6-8 hours or on high for 3-4 hours. So, if you plan ahead, you can set it in the morning and come home to a delicious meal!

Step-by-Step Instructions:

1. Mix the Meatloaf Ingredients:

In a large bowl, mix the ground beef, breadcrumbs, chopped onion, minced garlic, eggs, milk, Dr. Pepper, ketchup, Worcestershire sauce, salt, pepper, thyme, oregano, and smoked paprika together. Use your hands or a spoon, being careful not to over-mix. Just blend it until everything is combined!

2. Shape the Meatloaf:

Take the meat mixture and form it into a loaf shape. Make sure it fits comfortably in your slow cooker.

3. Prepare the Glaze:

In a small bowl, whisk together the glaze ingredients: ketchup, Dr. Pepper, brown sugar, and optional Dijon mustard until it’s all smooth and well combined.

4. Cook the Meatloaf:

Place the meatloaf in the crockpot and evenly spread about half of the glaze over the top. Cover the crockpot and cook! Choose low for 6-8 hours or high for 3-4 hours, until the meatloaf reaches an internal temperature of 160°F (71°C).

5. Finish with a Glaze:

About 30 minutes before you plan to serve, spread the remaining glaze on top of the meatloaf to make it sticky and delicious!

6. Serve and Enjoy:

Once it’s cooked, carefully remove the meatloaf from the crockpot and transfer it to a serving plate. Garnish with fresh parsley, slice it up, and serve it hot! It pairs wonderfully with mashed potatoes and steamed veggies.

Enjoy this tender, flavorful meatloaf with its sweet and tangy Dr. Pepper glaze. It’s a delightful twist on a classic dish!

Can I Use Leaner Ground Beef for This Meatloaf?

Yes, you can use leaner ground beef, like 90/10, but be aware that it may result in a drier meatloaf. To compensate for the lack of fat, you could add an extra tablespoon of milk or a bit more Dr. Pepper to keep it moist.

Can I Make This Meatloaf Gluten-Free?

Absolutely! Just swap out regular breadcrumbs for gluten-free breadcrumbs or crushed gluten-free crackers. The rest of the ingredients are naturally gluten-free, but always double-check labels to ensure they are safe.

How Do I Store Leftovers?

Store any leftover meatloaf in an airtight container in the refrigerator for up to 4 days. You can also freeze slices wrapped tightly in plastic wrap and foil for up to 3 months. To reheat, thaw overnight in the fridge and warm in the oven or microwave until heated through.

Can I Cook This Meatloaf in the Oven Instead?

Yes! Preheat your oven to 350°F (175°C) and place the shaped meatloaf in a greased baking dish. Bake for about 1 hour, or until it reaches an internal temperature of 160°F (71°C), brushing with the glaze during the last 15 minutes for extra flavor.

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